Reagents for Sysmex hemostasis analyzers
Sysmex Corporation. Japan
Screening coagulogram
Prothrombin time: Innovin, Thromborel® S (adaptations for instruments: CA 104, CA-620/660, CS-1600/2000/2400, CN-3000/6000).
Activated Partial Thromboplastin Time (APTT): Actin, Actin FS, Actin FSL (CA-104, CA-620/660, CS-1600/2000/2400, CN-3000/6000), Pathromtin SL (CS-1600/2000/2400, CN-3000/6000).
Thrombin Time: Test Thrombin Reagent (CA-104, CA-620/660, CS 1600/2000/2400, CN-3000/6000).
Fibrinogen: Multifibren® U (CA-104, CA 620/660), Dade® Thrombin (CA-620/660, CS-1600/2000/2400, CN-3000/6000).
Diagnosis of thrombophilia
Lupus anticoagulant: LA 1 Screening Reagent, LA 2 Confirmation Reagent (CA-104, CA-620/660, CS 1600/2000/2400, CN-3000/6000).
Antithrombin activity: Berichrom Antithrombin III (CA-660, CS 1600/2000/2400, CN-3000/6000)
Protein C activity: Berichrom Protein C (CA-660, CS-1600/2000/2400, CN 3000/6000).
Activated Protein C Resistance: ProC Ac R (CS-1600/2000/2400, CN-3000/6000)
Protein S Activity: Protein S Ac Reagent (CS-1600/2000/2400, CN-3000/6000)
D-dimer: INNOVANCE® D-Dimer (CA-660, CS-1600/2000/2400, CN-3000/6000)
Activity of blood coagulation factors
Factor II activity: Clotting Factor II Deficient Plasma
Factor V activity: Clotting Factor V Deficient Plasma
Factor VII activity: Clotting Factor VII-Deficient Plasma
Factor VIII activity: Clotting Factor VIII-Deficient Plasma
Factor IX activity: Clotting Factor IX Deficient Plasma
Factor X activity: Clotting Factor X Deficient Plasma
Factor XI activity: Clotting Factor XI Deficient Plasma
For CA, CS, and CN series analyzers
Reagents from Siemens Healthineers (Germany) and HYPHEN BioMed (France) for Sysmex CA, CS, and CN series hemostasis analyzers
Screening coagulogram
Diagnosis of thrombophilia
D-dimers
Assessment of fibrinolysis
Monitoring of heparin therapy
Monitoring of therapy with direct oral anticoagulants
Activity of blood coagulation factors
Von Willebrand disease
Functional activity of platelets
Functional activity of platelets
D-dimer test
D-dimer: INNOVANCE® D-Dimer (CA-660, CS-1600/2000/2400, CN-3000/6000).
Assessment of fibrinolysis
Plasminogen activity: Berichrom Plasminogen
Alpha-2-Antiplasmin activity: Berichrom a2-Antiplasmin
C1 inhibitor activity: Berichrom C1 Inhibitor
D-dimer: INNOVANCE® D-Dimer. Adaptations for the following instruments: CA-660, CS 1600/2000/2400, CN-3000/6000.
Monitoring of heparin therapy
Unfractionated heparin: Biophen Heparin LRT
Low-molecular-weight heparin: Biophen Heparin LRT. Instrument adaptations: CA-620/660, CS 1600/2000/2400, CN-3000/6000
Monitoring of therapy with direct oral anticoagulants
Rivaroxaban (Xarelto): Biophen Heparin LRT
Apixaban (Eliquis): Biophen Heparin LRT
Edoxaban (Lixiana): Biophen Heparin LRT
Dabigatran (Pradaxa): Biophen Heparin LRT. Adaptations for the following instruments: CS 1600/2000/2400, CN-3000/6000.
Von Willebrand disease
von Willebrand factor activity: INNOVANCE VWF Ac (CA-660, CS 1600/2000/2400, CN-3000/6000)
Ristocetin cofactor activity: Ristocetin reagent (CS-2000/2400, CN 3000/6000)
Functional activity of platelets
Aggregation inducers: ADP Reagent (Adenosine-5'-diphosphate), Collagen Reagent, Epinephrine Reagent, Arachidonic Acid Reagent, ADP Reagent (Adenosine-5'-diphosphate), Ristocetin Reagent. Adaptation for instruments: CS-2000/2400, CN 3000/6000
Assessment of the efficacy of antiplatelet therapy: aspirin, clopidogrel. Adaptation for the following instruments: CS-2000/2400, CN-3000/6000
Factor XII activity: Clotting Factor XII-Deficient Plasma. Instrument adaptations: CA-104, CA 620/660, CS-1600/2000/2400, CN 3000/6000