Sysmex XN-1500 Hematology Station
Sysmex Corporation. Japan
Modular hematology station with smear preparation and staining capabilities
It is complemented by an integrated module for the preparation and staining of smears, which adapts to the laboratory's needs.
An integrated system of rules ensures increased efficiency in smear analysis and reduces the time it takes for results to become available to the physician.
An integrated system of rules ensures increased efficiency in smear analysis and reduces the time it takes for results to become available to the physician.
The DI-60 optional module for digital imaging and automated cell identification will allow for the efficient use of medical staff's time.
DESIGNED FOR VERSATILITY
The XN-1500 hematology station ensures standardization of the entire complete blood count process and includes a stage for the preparation and staining of blood smears.
The station includes an automated hematology analysis module, which can be equipped with all the diagnostic capabilities of the XN series.
The modular design of the analyzer allows for the functional rationalization of the scope of microscopy performed—using a system of rules—and enables the adaptation of the examination algorithm specifically for each individual sample.
The SP-50 smear staining module can be used independently for the preparation of peripheral blood smears, as well as for the staining of bone marrow smears.
Overall management of the XN 1500 is handled by the Extended IPU station, which regulates all processes related to the execution of analysis, including the analytical procedure, biological validation, and interpretation.
Configurations
XN-1500 (DIFF) – гематологічна станція, що складається з 2-х модулів: модуль автоматичного гематологічного аналізу XN 10 і модуль автоматичного приготування та забарвлення мазків SP-50
The XN-1500 (WPC) is a hematology station consisting of two modules: the XN-20 automated hematology analysis module and the SP-50 automated slide preparation and staining module.
Methods and Technologies
WBC DIFF/RET/PLT-F/WPC: Flow cytometry
RBC/PLT: Hydrodynamic focusing with the impedance method
HGB (hemoglobin): Cyanide-free SLS method
Preparation of Smears: Wedge Method
Smear Staining Protocols: Romanowsky-Giemsa, Wright-Giemsa, and Wright Methods
Image analysis system (optional): Digital microscopy method with image analysis using artificial neural networks
Diagnostic modules
XN-10 Automated Hematology Analysis Module (XN-1500 (DIFF) configuration)
1. Basic CBC+DIFF mode
2. Optional diagnostic channels:
RET channel (analysis of reticulocytes and reticulocyte parameters)
PLT-F channel (fluorescent platelet analysis with assessment of the immature platelet fraction)
BF channel (cytological analysis of body fluids)
XN-20 Automated Hematology Analyzer Module (XN-1500 (WPC) configuration):
1. Basic mode: CBC+DIFF, RET channel (analysis of reticulocytes and reticulocyte parameters), WPC channel (channel for diagnosing neoplastic processes and counting hematopoietic precursor cells)
2. Optional diagnostic channels:
PLT-F channel (fluorescent platelet analysis with assessment of the immature platelet fraction)
BF channel (cytological analysis of body fluids)
SP-50 Automatic Smear Preparation and Staining Module
DI-60 module for digital imaging and morphological analysis of blood cells and body fluids (optional)
CHARACTERISTICS
Measurement principle
WBC/DIFF/RET/PLT-F/WPC: Fluorescent flow cytometry
RBC/PLT: Impedance method with hydrodynamic focusing
HGB (Hemoglobin): Cyanide-free SLS method
CBC+DIFF mode parameters
WBC, NRBC%, NRBC#, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, MicroR%, MacroR%, PDW, MPV, P-LCR, PCT, NEUT%, NEUT#, LYMPH%, LYMPH#, MONO%, MONO#, EO%, EO#, BASO%, IG#
Optional: extended inflammation parameters (Extended Inflammation Parameters license): NEUT-GI, NEUT-RI, RE-LYMP%, RE-LYMP#, AS-LYMP%, AS LYMP#
Optional: TNC, TNC-C, TNC-D, WBCC, WBC-D, NE-SSC, NE-SFL, NEFSC, HFLC#, HFLC%
RET channel parameters
RET%, RET#, IRF, LFR, MFR, HFR, RET-He, RBC-He, Delta-He, HYPO-He%, HYPER He%, PLT-O
Additional: FRC#, FRC%, RPI, RBC-O, HGB O, MCHC-O
PLT-F-channel parameters
WPC channel parameters
BF channel parameters
Throughput capacity
Sample aspiration volume
Device memory
Quality Control
Reagents
Dimensions
PLT-F, IPF, IPF#
Highly specific marker for neoplastic processes
Optional: stem cell count (XN Stem Cells licence): HPC%, HPC#
Main: WBC-BF, RBC-BF, MN%, MN#, PMN%, PMN#, TC-BF#
HF-BF#, HF-BF%, NE-BF#, NE BF%, LY-BF#, LY-BF%, MOBF#, MO-BF%, EO-BF#, EO-BF%, RBC-BF-2
CBC+DIFF – complete blood count (CBC) mode with a 7-part white blood cell (WBC) differential: 100 samples/hour
CBC+DIFF+RET – complete blood count (CBC) mode with a 7-part white blood cell (WBC) differential and reticulocyte analysis: 83 samples/hour
BF analysis – cytological examination of body fluids: 40 samples/hour
Hematology analysis module (XN 10/20): 88 µL of venous or capillary blood with EDTA for CBC+DIFF, CBC+DIFF+RET, and CBC+DIFF+RET+PLT-F modes
88 µL of a biological fluid sample for the BF analysis mode
Smear preparation and staining module: 70 µL of whole blood with EDTA for the automatic sample feed mode, and 35 µL of blood with EDTA for the manual sample feed mode
1. Complete test results – from 100,000 samples
2. Patient information – 100,000 records
3. Quality control information, 300 charts per file:
QC: 99 files
X-bar controls (L-J charts): 94 files
X-barM controls: 5 files
4. Reagent replacement history: 5,000 records
XN CHECK L1, XN CHECK L2, XN CHECK L3: Material (3 levels) for quality control of all parameters measured in CBC+DIFF+RET mode. Pack size: 3 ml per level.
XN Check BF: Material (2 levels) for quality control of all parameters measured in CBC+DIFF+RET mode. Pack size: 3 ml per level.
SVS+DIFF mode, BF mode
CELLPACK DCL 10/20 l
SULFOLYSER 3 x 500 ml / 5 l
LYSERCELL WDF 2 l
FLUOROCELL WDF 2 x 22 ml
LYSERCELL WNR 5L
FLUOROCELL WNR 2X82ML
CELLCLEAN 50 ml
RET mode
CELLPACK DFL 2 x 1.5 l
FLUOROCELL RET 2 x 12 ml
PLT-F mode
CELLPACK DFL 2 x 1.5 l
Fluorocell PLT 2 x 12 ml
WPC mode
Lysercell WPC 2 x 1.5 l
Fluorocell WPC 2 x 12 ml
Station, including 2 modules (XN-10/20 and SP-50) and a common automatic sample loader: 1006 x 1053 x 855 mm / 211 kg